Generic Zestoretic (Lisinopril / Hydrochlorothiazide)
Zestoretic
Zestoretic is a combination of a diuretic and an ACE inhibitor indicated to treat high blood pressure.
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5/12.5 g/mg x 30 pills
$59.99
$2.00
$0.00
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5/12.5 g/mg x 60 pills
$95.99
$1.60
$24.00
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5/12.5 g/mg x 90 pills
$129.99
$1.44
$50.40
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5/12.5 g/mg x 120 pills
$155.99
$1.30
$84.00
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5/12.5 g/mg x 180 pills
$209.99
$1.17
$149.40
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5/12.5 g/mg x 360 pills
$377.99
$1.05
$342.00
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Product Description
Common use

Zestoretic is a combination of two drugs. Hydrochlorothiazide is a thiazide diuretic medication while Lisinopril belongs to the class of drugs called ACE inhibitors. The first prevents body from absorbing too much salt, which can cause fluid retention, and the second lowers blood pressure and also relieves symptoms of fluid retention.



Dosage and direction

Take exactly as it was prescribed to you, do not change your dose without your doctor's permission. Take each dose with a glass of water regardless to a meal.



Precautions

Avoid drinking alcohol. Avoid salt substitutes containing potassium. If you have disorders of liver or kidney, lupus, asthma, gout, diabetes, congestive heart failure or pregnant consult your doctor first than to take Zestoretic. While you are taking Zestoretic, your blood pressure will need to be checked regularly.



Contraindications

Anuria, hypersensitivity to the components of Zestoretic, in patients who had angioedema (swelling of face, extremities, eyes, lips, tongue, difficulty in swallowing or breathing) in their history.



Possible side effect

Seek for immediate medical help if such symptoms are observed while taking Zerstoretic: high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling), low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling), thirst, nausea, vomiting, dry mouth, drowsiness, skin rash jaundice urinating less than usual swelling, weight gain and any serious symptom of allergy (hives, swelling of your face, lips, tongue, or throat).



Drug interaction

NSAIDs may diminish the antihypertensive effect of ACE inhibitors. When Zestoretic is administered concomitantly with non-steroidal anti-inflammatory drugs in patients with compromised renal function the further deterioration of renal function may occur. Use of Zestoretic with potassium-sparing diuretics may lead to significant increases in serum potassium. Zestoretic increases lithium toxicity, may influence when cholestyramine and gold injections are used for treatment of certain diseases.



Missed dose

If you missed a dose take it as soon as you remember, but if it is almost time of your next intake just skip the missed dose. Do not try to compensate a missed dose by taking an extra one.



Overdose

If you suspect that you took too much of Zestoretic and experience nausea, weakness, dizziness, dry mouth, thirst, muscle pain or weakness seek for immediate medical attention.



Storage

The medication should be stored at room temperature 15-30 C (59-86 F) in a light- resistant box.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Accutane

Other names used:

  • Roaccutane®

Active Ingredients:

  • Isotretionin

How does Accutane work and what pharmaceutical group does it belong to?

Isotretionin the active ingredient of Accutane belongs to a group of drugs called retinoids, which are used mainly in treatment of skin disorders. The exact mechanism of Accutane is not currently known however it is clinically determined that the drug exerts dose-dependent suppressive effect on the sebaceous glands activity and decreases their size. The drug also expresses anti-inflammatory effect on skin as well as inhibits the formation of comedones. The effects of the drug are temporary however the acne remissions may be controlled.

Which conditions are treated with Isotretinoin?

The drug is indicated in treatment of:

  • Severe cystic acne vulgaris
  • Acne rosacea
  • Hidradenitis suppurativa

What should a patient know before using Accutane?

The Isotretinoin should not be used in cases of:

  • Known hypersensitivity to any components of the preparation or to other retinoids
  • Pregnancy
  • Liver or renal failure
  • Vitamin A hypervitaminosis
  • Severe hyperlipidemia

Tell your doctor about the following if any apply to you:

  • You have relatives with increased levels of lipids in blood and are predisposed to hyperlipidemia
  • You or your relatives suffer from diabetes
  • You are suffering from Alcoholism
  • You are treating a depression

Which adverse effects may manifest when using the medication?

The side effects of Accutane include:

  • Vitamin A hypervitaminosis manifested in the following: dry skin and mucous membranes, haemorrhage in the nasal cavity, hoarseness, conjunctivitis and etc.
  • Skin problems: rash, itching, facial dermatitis, sweatiness, hyperpigmentation, reversible allopecia and etc.
  • Locomotor system: muscle pain, joint pain, hyperostosis, tendonitis
  • CNS: behavior changes, depression, headache, increased intracranial pressure, seizures
  • Sensory organs: decreased vision acuity, photosensibilisation, cataract, decreased hearing , keratitis
  • Gastrointestinal tract: nausea, colitis, GI hemorrhage, rarely hepatitis.
  • Respiratory organs: bronchospasm
  • Haemopoietic system: decreased leukocyte and erythrocyte levels, increase or decrease of thrombocyte levels
  • Immune system: local or systemic infections caused be gram-positive bacteria
  • Other: Hematuria, pancreatitis, vasculitis, lymphadenopathy

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Isotretinoin?

The drug is affected by the following:

  • Vitamin A supplements
  • Corticosteroids
  • Tetracycline antibiotics
  • Epilepsy treatment
  • Oral contraceptives
  • St.John's worth

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient: Accutane is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.