Generic Ortho Tri-Cyclen (Norgestimate / Ethinyl estradiol)
Ortho Tri-Cyclen
Ortho Tri-Cyclen is a formulation of female hormones used orally to prevent pregnancy.
Package
Price
Per Pills
Savings
Bonus
Order
50 mg x 84 pills
$100.99
$1.20
$0.00
Next orders 10% discount
50 mg x 168 pills
$160.99
$0.96
$40.32
Next orders 10% discount
50 mg x 252 pills
$217.99
$0.87
$83.16
Next orders 10% discount
Free standard airmail service
50 mg x 672 pills
$522.99
$0.78
$282.24
Next orders 10% discount
Free standard airmail service
Product Description
Common use

Ortho Tri-Cyclen contains estrogenic compound ethinyl estradiol and norgestimate, a synthetic form of progesterone or a progestin (female hormone) which prevents ovulation and participates in regulation of menstruation. Progesterone is produced in an ovary after an egg matured and was released from it to prevent the release of further eggs. In case of pregnancy levels of progesterone in blood remain high maintaining the womb lining. Thus this hormone 'tricks' the body informing it that ovulation has already occurred and this way it may be used as contraception to prevent pregnancy. Ortho Tri-Cyclen impedes sperm cells to reach the uterus acting on cervical mucus and uterine lining and makes it more difficult for a fertilized egg to adhere to the uterus. It can also be used to treat severe achne.



Dosage and direction

Follow all doctor's instructions regarding take of Ortho Tri-Cyclen. Never take it in larger amounts or take it longer than recommended. Take the first 'active' pill on the first day of your monthlies or on the first Sunday after your menstruation starts. Take one pill every day, desirably at the same time each day. When 'active' pills from the 28-day birth control pack are over take seven "reminder" pills (one tablet each day) to keep you on your regular cycle. Your monthlies usually starts while you are using these 'reminder' tablets.



Precautions

Avoid smoking cigarettes/using tobacco while using hormonal birth control pills due to increased risk of heart problems and stroke. The risk of heart diseases also aggravates with age (especially in women over 35 y.o.) and in those who smoker more than 15 cigarettes daily. Notify your doctor if you had in your history such conditions as: blood clotting, stroke, problems with circulation, a hormone-related cancer (breast or uterine cancer), unusual vaginal bleeding, liver malfunctions and diseases or malignant or benign liver tumors, jaundice caused by birth control pills. This drug cannot be used in pregnant women. Inform your surgeon if you are taking Ortho Tri-Cyclen as you may need to stop its intake.



Contraindications

Ortho Tri-Cyclen is contraindicated in patients who have suffered with thrombophlebitis or thromboembolic disorders (including deep vein thrombophlebitis or thromboembolic in history), cerebral vascular or coronary artery disease, migraine, carcinoma of the breast, estrogendependent neoplasia, undiagnosed abnormal genital bleeding, jaundice caused by cholestasis or a prior pill use, acute or chronic hepatocellular disease with abnormal liver function, adenomas or carcinomas in the liver, or in patients who are pregnant or hypersensitive to Ortho Tri-Cyclen.



Possible side effect

In case of allergic reaction caused by this medication (hives, swelling of face and tongue, rash) contact your doctor immediately. Other side effects may include nausea, vomiting, headache, stomach cramping/bloating, dizziness, vaginal discomfort/irritation, increased vaginal fluids, or breast tenderness/enlargement may occur. Acne may resolve or get worse. Vaginal bleeding between periods or irregular periods may occur, especially during the first months of treatment. This medication may rarely cause serious and in rare cases fatal problems from blood clots. If you noticed any of such symptoms stop taking Ortho Tri-Cyclen and seek for immediate medical attention.



Drug interaction

Decrease of contraceptive effect occur if Ortho Tri-Cyclen is concomitantly used with antibiotics, anticonvulsants, and other drugs that increase the metabolism of contraceptive steroids. Interaction is possible between Ortho Tri-Cyclen and phenylbutazone (Azolid, Butazolidin), St. John's wort, seizure medicines such as phenytoin (Dilantin), topiramate (Topamax), carbamazepine (Tegretol), oxcarbazepine (Trileptal); barbiturates such as butabarbital (Butisol), secobarbital (Seconal), amobarbital (Amytal), phenobarbital (Luminal, Solfoton), mephobarbital (Mebaral); HIV medicines. Ascorbic acid and acetaminophen also are able to increase plasma ethinyl estradiol levels.



Missed dose

If you missed a pill risk of becoming pregnant increases. If you forgot to take one 'active' pill, take two pills as soon as you remember then return to your schedule. If you miss two 'active' pills in a row in first or second week of treatment, take two pills a day for two days in a row. Then return to your schedule. Use birth control test during seven days if such a 'mistake' occurred. If you miss two 'active' pills in a row during third week, or if you miss three pills in a row during any of the first three weeks, you need to start a new pack of pills as if you are a First Day starter.

If you did not take three 'active' pills in a row during any of the first three weeks, start a new pack on the same day as if you are a First Day starter.

If you skipped intake of two or more pills, you may not have a monthlies during this month. If you miss a period for two months in a row you might be pregnant.

If you miss any reminder pills, throw the missed pills away and return to your schedule.



Overdose

If you suspect that you took too much of the medication seek for immediate medical attention and drink glass of milk. Possible overdose symptoms include nausea, vomiting, and vaginal bleeding.



Storage

Store Ortho Tri-Cyclen in a dry tight container away from sunlight at room temperature between 15-30 C (59-86 F) away from children and pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Accutane

Other names used:

  • Roaccutane®

Active Ingredients:

  • Isotretionin

How does Accutane work and what pharmaceutical group does it belong to?

Isotretionin the active ingredient of Accutane belongs to a group of drugs called retinoids, which are used mainly in treatment of skin disorders. The exact mechanism of Accutane is not currently known however it is clinically determined that the drug exerts dose-dependent suppressive effect on the sebaceous glands activity and decreases their size. The drug also expresses anti-inflammatory effect on skin as well as inhibits the formation of comedones. The effects of the drug are temporary however the acne remissions may be controlled.

Which conditions are treated with Isotretinoin?

The drug is indicated in treatment of:

  • Severe cystic acne vulgaris
  • Acne rosacea
  • Hidradenitis suppurativa

What should a patient know before using Accutane?

The Isotretinoin should not be used in cases of:

  • Known hypersensitivity to any components of the preparation or to other retinoids
  • Pregnancy
  • Liver or renal failure
  • Vitamin A hypervitaminosis
  • Severe hyperlipidemia

Tell your doctor about the following if any apply to you:

  • You have relatives with increased levels of lipids in blood and are predisposed to hyperlipidemia
  • You or your relatives suffer from diabetes
  • You are suffering from Alcoholism
  • You are treating a depression

Which adverse effects may manifest when using the medication?

The side effects of Accutane include:

  • Vitamin A hypervitaminosis manifested in the following: dry skin and mucous membranes, haemorrhage in the nasal cavity, hoarseness, conjunctivitis and etc.
  • Skin problems: rash, itching, facial dermatitis, sweatiness, hyperpigmentation, reversible allopecia and etc.
  • Locomotor system: muscle pain, joint pain, hyperostosis, tendonitis
  • CNS: behavior changes, depression, headache, increased intracranial pressure, seizures
  • Sensory organs: decreased vision acuity, photosensibilisation, cataract, decreased hearing , keratitis
  • Gastrointestinal tract: nausea, colitis, GI hemorrhage, rarely hepatitis.
  • Respiratory organs: bronchospasm
  • Haemopoietic system: decreased leukocyte and erythrocyte levels, increase or decrease of thrombocyte levels
  • Immune system: local or systemic infections caused be gram-positive bacteria
  • Other: Hematuria, pancreatitis, vasculitis, lymphadenopathy

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Isotretinoin?

The drug is affected by the following:

  • Vitamin A supplements
  • Corticosteroids
  • Tetracycline antibiotics
  • Epilepsy treatment
  • Oral contraceptives
  • St.John's worth

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient: Accutane is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.