Generic Microzide (Hydrochlorothiazide)
Microzide
Microzide is a diuretic used to lower blood pressure and prevent heart attacks, strokes, and kidney problems.
Package
Price
Per Pills
Savings
Bonus
Order
25 mg x 30 pills
$42.99
$1.43
$0.00
Next orders 10% discount
25 mg x 60 pills
$59.99
$1.00
$25.80
Next orders 10% discount
25 mg x 90 pills
$75.99
$0.84
$53.10
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25 mg x 120 pills
$91.99
$0.77
$79.20
Next orders 10% discount
25 mg x 180 pills
$123.99
$0.69
$133.20
Next orders 10% discount
25 mg x 240 pills
$147.99
$0.62
$194.40
Next orders 10% discount
25 mg x 360 pills
$179.99
$0.50
$334.80
Next orders 10% discount
Product Description
Common use

Microzide is a moderate thiazide diuretic medication which decreases reabsorbtion of Na+ at the level of cortical limb of Henles' loop not influencing its segment located in medullary layer of the kidney. This is a reason of its weaker diuretic effect comparing to Lasix. Microzide is used to treat high blood pressure and accumulation of fluid (edema of different origin). Mechanism of its treating effect on lowering of high blood pressure is not well understood.



Dosage and direction

Microzide maybe taken with our without food and its dose depends on your condition, age and weight and should be prescribed by your doctor.



Precautions

Avoid drinking alcohol, becoming overheated or dehydrated during workouts, exercise and in hot weather. Warn your doctor if you suffer from liver disease, kidney disease, asthma or allergies, gout, diabetes, or if you are allergic to sulfa drugs.



Contraindications

Hypersensitivity, diabetes, chronic kidney failure, anuria, severe liver failure Addison disease, first trimester of pregnancy, breastfeeding, infancy (younger than 3 y.o.).



Possible side effect

If you feel weakness, low blood pressure, light sensitivity, impotence, nausea, abdominal pain, electrolyte disturbances, pancreatitis, jaundice, anaphylaxis, and rashes contact your doctor and seek for immediate medical help. Patients allergic to Sulfa may also be allergic to Microzide.



Microzide can aggravate kidney dysfunction, lower blood potassium, sodium, and magnesium levels. Low potassium and magnesium levels can lead to abnormalities in heart rhythm, so treatment with Microzide require supplementation with potassium is common to prevent low potassium levels.



Drug interaction

Concomitant treatment with ethanol, barbiturates, opioid analgesics increases risk of hypotension. If Microzide is administered with insulin and medications which decrease levels of sugar in blood correction of such medication may be needed. Microzide reduces the elimination of lithium by the kidneys. Nonsteroidal antiinflammatory drugs may reduce the blood pressure effects of Microzide.



Missed dose

If you forgot to take a dose take it as soon as you remember. Skip the missed dose if it is almost time for the next intake. Resume your regular schedule. Do not compensate the missed dose by taking an extra one.



Overdose

If you experience nausea, weakness, dizziness, dry mouth, thirst, and muscle pain or weakness seek for immediate medical help.



Storage

Keep at room temperature, 15-30 C (59-86 F), in a light-resistant container away from moisture.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Accutane

Other names used:

  • Roaccutane®

Active Ingredients:

  • Isotretionin

How does Accutane work and what pharmaceutical group does it belong to?

Isotretionin the active ingredient of Accutane belongs to a group of drugs called retinoids, which are used mainly in treatment of skin disorders. The exact mechanism of Accutane is not currently known however it is clinically determined that the drug exerts dose-dependent suppressive effect on the sebaceous glands activity and decreases their size. The drug also expresses anti-inflammatory effect on skin as well as inhibits the formation of comedones. The effects of the drug are temporary however the acne remissions may be controlled.

Which conditions are treated with Isotretinoin?

The drug is indicated in treatment of:

  • Severe cystic acne vulgaris
  • Acne rosacea
  • Hidradenitis suppurativa

What should a patient know before using Accutane?

The Isotretinoin should not be used in cases of:

  • Known hypersensitivity to any components of the preparation or to other retinoids
  • Pregnancy
  • Liver or renal failure
  • Vitamin A hypervitaminosis
  • Severe hyperlipidemia

Tell your doctor about the following if any apply to you:

  • You have relatives with increased levels of lipids in blood and are predisposed to hyperlipidemia
  • You or your relatives suffer from diabetes
  • You are suffering from Alcoholism
  • You are treating a depression

Which adverse effects may manifest when using the medication?

The side effects of Accutane include:

  • Vitamin A hypervitaminosis manifested in the following: dry skin and mucous membranes, haemorrhage in the nasal cavity, hoarseness, conjunctivitis and etc.
  • Skin problems: rash, itching, facial dermatitis, sweatiness, hyperpigmentation, reversible allopecia and etc.
  • Locomotor system: muscle pain, joint pain, hyperostosis, tendonitis
  • CNS: behavior changes, depression, headache, increased intracranial pressure, seizures
  • Sensory organs: decreased vision acuity, photosensibilisation, cataract, decreased hearing , keratitis
  • Gastrointestinal tract: nausea, colitis, GI hemorrhage, rarely hepatitis.
  • Respiratory organs: bronchospasm
  • Haemopoietic system: decreased leukocyte and erythrocyte levels, increase or decrease of thrombocyte levels
  • Immune system: local or systemic infections caused be gram-positive bacteria
  • Other: Hematuria, pancreatitis, vasculitis, lymphadenopathy

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Isotretinoin?

The drug is affected by the following:

  • Vitamin A supplements
  • Corticosteroids
  • Tetracycline antibiotics
  • Epilepsy treatment
  • Oral contraceptives
  • St.John's worth

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient: Accutane is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.