Generic Mestinon (Pyridostigmine)
Mestinon
Mestinon is used to treat myasthenia gravis or intestinal atony and atonic constipation, it works increasing muscle tone of smooth muscles in different organs.
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60 mg x 30 pills
$72.99
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60 mg x 60 pills
$122.99
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60 mg x 90 pills
$166.99
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60 mg x 120 pills
$199.99
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60 mg x 180 pills
$269.99
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60 mg x 240 pills
$323.99
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Product Description
Common use

Mestinon contains pyridostigmine bromide and is used to treat myasthenia gravis. The medicine inhibits acetylcholinesterase and increases effects of acetylcholine. It improves neuromuscular transmission, increases gastrointestinal motility, increases muscle tone of the bladder, bronchi, and secretion of exocrine glands, causes bradycardia, miosis, spasm of accommodation.



Dosage and direction

To treat intestinal atony and atonic constipation take orally 60 mg every 4 hours, to treat acute myasthenia gravis use 60-180 mg of the medication 2-4 times a day. Te dose may be increased by your doctor. Swallow the pills whole, do not crush, chew or break extended-release tablets. Do not take double dose of this medication. Take your usually dose next day in the same regularly time.



Precautions

Inform your doctor if you have asthma or kidney disease. Your dose may be increased by your doctor. Follow all recommendations of your health care advisor. Inform your doctor about your hypotension, acute myocardial infarction, ulcers in stomach and duodenum, bradycardia, diabetes, stomach surgery, pregnancy.



Contraindications

This medication cannot be used in patients with peritonitis, and a bladder or bowel obstruction. Do not take Mestinon if you have been treated by depolarizing muscle relaxants (suxametone, dekametone), have hypersensitivity to Mestinon, suffer with iritis, asthma, obstructive ileus, a spasm of gastrointestinal tract, spasm of biliary or urinary tract, myotonia, Parkinson's disease, thyrotoxicosis (excess thyroid hormone production), post-operative shock, in pregnant women.



Possible side effect

Allergic reactions to the medication are possible, their symptoms include hives, skin rash, difficulty breathing, facial swelling. More serious adverse reactions are severe nausea, vomiting or diarrhea, extreme muscle weakness, problems with vision, muscle cramps or twitching, drop in blood pressure, excessive salivation, frequent urination, drop in blood pressure, bradycardia, miosis, convulsions, muscle twitching, myasthenia gravis.



Drug interaction

Atropine reduces effects of Mestinon. Mestinon used together with the depolarizing muscle relaxants, barbiturates and morphine derivatives increases their effects. Mestinon is contraindicated for use with ethanol. M-cholinoblockers, ganglioplegic drugs, quinidine, procainamide, local anesthetics, tricyclic antidepressants, antiepileptic drugs, and drugs for Parkinson's disease decrease effects of Mestinon.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose.



Overdose

Signs of overdose are nausea, vomiting, extreme muscle weakness, diarrhea, sweating, and muscle cramps, or weakness, involuntary defecation and urination, intestinal colic. Contact your doctor immediately if you experience any of the symptoms listed in this section.



Storage

Store in a dry tight container away from sunlight at room temperature between 15-30 C (59-86 F) away from children and pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Accutane

Other names used:

  • Roaccutane®

Active Ingredients:

  • Isotretionin

How does Accutane work and what pharmaceutical group does it belong to?

Isotretionin the active ingredient of Accutane belongs to a group of drugs called retinoids, which are used mainly in treatment of skin disorders. The exact mechanism of Accutane is not currently known however it is clinically determined that the drug exerts dose-dependent suppressive effect on the sebaceous glands activity and decreases their size. The drug also expresses anti-inflammatory effect on skin as well as inhibits the formation of comedones. The effects of the drug are temporary however the acne remissions may be controlled.

Which conditions are treated with Isotretinoin?

The drug is indicated in treatment of:

  • Severe cystic acne vulgaris
  • Acne rosacea
  • Hidradenitis suppurativa

What should a patient know before using Accutane?

The Isotretinoin should not be used in cases of:

  • Known hypersensitivity to any components of the preparation or to other retinoids
  • Pregnancy
  • Liver or renal failure
  • Vitamin A hypervitaminosis
  • Severe hyperlipidemia

Tell your doctor about the following if any apply to you:

  • You have relatives with increased levels of lipids in blood and are predisposed to hyperlipidemia
  • You or your relatives suffer from diabetes
  • You are suffering from Alcoholism
  • You are treating a depression

Which adverse effects may manifest when using the medication?

The side effects of Accutane include:

  • Vitamin A hypervitaminosis manifested in the following: dry skin and mucous membranes, haemorrhage in the nasal cavity, hoarseness, conjunctivitis and etc.
  • Skin problems: rash, itching, facial dermatitis, sweatiness, hyperpigmentation, reversible allopecia and etc.
  • Locomotor system: muscle pain, joint pain, hyperostosis, tendonitis
  • CNS: behavior changes, depression, headache, increased intracranial pressure, seizures
  • Sensory organs: decreased vision acuity, photosensibilisation, cataract, decreased hearing , keratitis
  • Gastrointestinal tract: nausea, colitis, GI hemorrhage, rarely hepatitis.
  • Respiratory organs: bronchospasm
  • Haemopoietic system: decreased leukocyte and erythrocyte levels, increase or decrease of thrombocyte levels
  • Immune system: local or systemic infections caused be gram-positive bacteria
  • Other: Hematuria, pancreatitis, vasculitis, lymphadenopathy

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Isotretinoin?

The drug is affected by the following:

  • Vitamin A supplements
  • Corticosteroids
  • Tetracycline antibiotics
  • Epilepsy treatment
  • Oral contraceptives
  • St.John's worth

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient: Accutane is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.