Generic Duphaston (Dydrogesterone)
Duphaston
Duphaston is a synthetic hormone applied in treatment of secondary amenorrhoea, dysfunctional uterine bleeding and post-menopausal symptoms.
Package
Price
Per Pills
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Order
10 mg x 10 pills
$47.99
$4.80
$0.00
Next orders 10% discount
10 mg x 20 pills
$76.99
$3.85
$19.00
Next orders 10% discount
10 mg x 30 pills
$97.99
$3.27
$45.90
Next orders 10% discount
10 mg x 60 pills
$155.99
$2.60
$132.00
Next orders 10% discount
10 mg x 90 pills
$210.99
$2.34
$221.40
Next orders 10% discount
Free standard airmail service
10 mg x 120 pills
$252.99
$2.11
$322.80
Next orders 10% discount
Free standard airmail service
Product Description
Common use

Duphaston contains dydrogesterone, a synthetic hormone similar to progesterone. The medication is used to restore the hormone balance when synthesis of progesterone in the body is not sufficient (sterility, abortion, premenstrual syndrome, dysmenorrhea, irregular menstruation, secondary amenorrhea, dysfunctional uterine bleeding). The medication stimulates beginning of the secretory phase in the endometrium thereby reducing the risk of endometrial hyperplasia and carcinogenesis, which increases due to estrogen.



Dosage and direction

Each condition requires special treatment and dose schedule. Follow all instructions of your doctor. To treat endometriosis take 10 mg of Duphaston two or three times a day from 5th to 25th day of your cycle. To treat infertility take 10 mg a day from 14th to 25th day of your cycle. The treatment should be done continuously for three, six and more following cycles. Contact your doctor about all details.



Precautions

Inform your doctor if you are pregnant or breastfeeding before to take this medication. Hormone replacement therapy should not be administered without a general medical examination, including pelvic examination. Your doctor may ask you to make mammogram examination regularly.



Contraindications

This medication cannot be used in individuals with hypersensitivity to Duphaston, Dubin-Johnson syndrome (an increase of conjugated bilirubin without elevation of liver enzymes), Rotor syndrome (a benign autosomal recessive bilirubin disorder).



Side effects

The most frequent adverse reactions include headache, nausea, dizziness, bloating, skin reactions (rash and itching), breast tenderness, menstrual spotting between periods



Drug interaction

Inductors of microsomal liver enzymes such as phenobarbital may accelerate the metabolism of Duphaston and weaken its effect.



Missed dose

If you forgot to take a dose contact your doctor about necessary actions.



Overdose

There is not information about possible overdose. Seek immediate medical help if you suspect overdose.



Storage

Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Accutane

Other names used:

  • Roaccutane®

Active Ingredients:

  • Isotretionin

How does Accutane work and what pharmaceutical group does it belong to?

Isotretionin the active ingredient of Accutane belongs to a group of drugs called retinoids, which are used mainly in treatment of skin disorders. The exact mechanism of Accutane is not currently known however it is clinically determined that the drug exerts dose-dependent suppressive effect on the sebaceous glands activity and decreases their size. The drug also expresses anti-inflammatory effect on skin as well as inhibits the formation of comedones. The effects of the drug are temporary however the acne remissions may be controlled.

Which conditions are treated with Isotretinoin?

The drug is indicated in treatment of:

  • Severe cystic acne vulgaris
  • Acne rosacea
  • Hidradenitis suppurativa

What should a patient know before using Accutane?

The Isotretinoin should not be used in cases of:

  • Known hypersensitivity to any components of the preparation or to other retinoids
  • Pregnancy
  • Liver or renal failure
  • Vitamin A hypervitaminosis
  • Severe hyperlipidemia

Tell your doctor about the following if any apply to you:

  • You have relatives with increased levels of lipids in blood and are predisposed to hyperlipidemia
  • You or your relatives suffer from diabetes
  • You are suffering from Alcoholism
  • You are treating a depression

Which adverse effects may manifest when using the medication?

The side effects of Accutane include:

  • Vitamin A hypervitaminosis manifested in the following: dry skin and mucous membranes, haemorrhage in the nasal cavity, hoarseness, conjunctivitis and etc.
  • Skin problems: rash, itching, facial dermatitis, sweatiness, hyperpigmentation, reversible allopecia and etc.
  • Locomotor system: muscle pain, joint pain, hyperostosis, tendonitis
  • CNS: behavior changes, depression, headache, increased intracranial pressure, seizures
  • Sensory organs: decreased vision acuity, photosensibilisation, cataract, decreased hearing , keratitis
  • Gastrointestinal tract: nausea, colitis, GI hemorrhage, rarely hepatitis.
  • Respiratory organs: bronchospasm
  • Haemopoietic system: decreased leukocyte and erythrocyte levels, increase or decrease of thrombocyte levels
  • Immune system: local or systemic infections caused be gram-positive bacteria
  • Other: Hematuria, pancreatitis, vasculitis, lymphadenopathy

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Isotretinoin?

The drug is affected by the following:

  • Vitamin A supplements
  • Corticosteroids
  • Tetracycline antibiotics
  • Epilepsy treatment
  • Oral contraceptives
  • St.John's worth

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient: Accutane is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.