Generic Avapro (Irbesartan)
Avapro
Avapro is used to treat hypertension and kidney problems (diabetic nephropathy) caused by diabetes.
Package
Price
Per Pills
Savings
Bonus
Order
150 mg x 10 pills
$18.99
$1.90
$0.00
Next orders 10% discount
150 mg x 30 pills
$45.99
$1.53
$11.10
Next orders 10% discount
150 mg x 60 pills
$82.99
$1.38
$31.20
Next orders 10% discount
150 mg x 90 pills
$111.99
$1.24
$59.40
Next orders 10% discount
150 mg x 120 pills
$133.99
$1.12
$93.60
Next orders 10% discount
150 mg x 180 pills
$166.99
$0.93
$174.60
Next orders 10% discount
Package
Price
Per Pills
Savings
Bonus
Order
300 mg x 10 pills
$19.99
$2.00
$0.00
Next orders 10% discount
300 mg x 30 pills
$49.99
$1.67
$9.90
Next orders 10% discount
300 mg x 60 pills
$91.99
$1.53
$28.20
Next orders 10% discount
300 mg x 90 pills
$126.99
$1.41
$53.10
Next orders 10% discount
300 mg x 120 pills
$155.99
$1.30
$84.00
Next orders 10% discount
300 mg x 180 pills
$212.99
$1.18
$147.60
Next orders 10% discount
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Product Description
Common use

Antihypertensive drug, antagonist of angiotensin receptors II. It specifically and irreversibly blocks receptors of angiotensin which leads to diminishing of biological effects of angiotensin II. Angiotensin II effects include vasoconstriction and stimulating influence on excretion of aldosterone and activation of sympathetic nervous system. As a consequence arterial pressure diminishes and the heart does not have to work as hard to pump blood. It does not influence concentration or triglycerides, content of cholesterol, glucose, uric acid in blood plasma and excretion of uric acid with urine.



Dosage and direction

Initial dose is 150 mg and it can be increased up to 300 mg on necessity. In some cases as low chloride diet, treatment with certain diuretics and others initial dose size should be smaller. Avapro is taken once a day preferably at the same time.



Precautions

It should be administered with kidney or liver failure, congestive heart failure, after strong vomit or diarrhea and also during simultaneous treatment with potassium saving diuretics or medications containing potassium. This drug causes serious harm to unborn baby (possibly death) if it is administered and used during the last six months of pregnancy.



Contraindications

Pregnancy, infancy, hypersensitivity to Avapro.



Possible side effect

The most common side effects include diarrhea, abdominal pain or heartburn. In case you experience allergic reaction to the medication (fever, difficult breathing, hives) contact your doctor. Avapro can cause a condition that results in the breakdown of skeletal muscle tissue and then in kidney failure. Also call your doctor if you have muscle pain, tenderness, or weakness especially if you also have vomiting, and dark colored urine, difficult urination.



Drug interaction

No important drug interactions were described for this medication. At simultaneous intake with potassium-saving diuretics level of potassium may increased in blood plasma.



Missed dose

Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.



Overdose

Immediate medical help is needed in case of overdose which symptoms include fast or slow heartbeat, dizziness.



Storage

Tablets should be stored at room temperature, 15-30 C (59-86 F).



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Accutane

Other names used:

  • Roaccutane®

Active Ingredients:

  • Isotretionin

How does Accutane work and what pharmaceutical group does it belong to?

Isotretionin the active ingredient of Accutane belongs to a group of drugs called retinoids, which are used mainly in treatment of skin disorders. The exact mechanism of Accutane is not currently known however it is clinically determined that the drug exerts dose-dependent suppressive effect on the sebaceous glands activity and decreases their size. The drug also expresses anti-inflammatory effect on skin as well as inhibits the formation of comedones. The effects of the drug are temporary however the acne remissions may be controlled.

Which conditions are treated with Isotretinoin?

The drug is indicated in treatment of:

  • Severe cystic acne vulgaris
  • Acne rosacea
  • Hidradenitis suppurativa

What should a patient know before using Accutane?

The Isotretinoin should not be used in cases of:

  • Known hypersensitivity to any components of the preparation or to other retinoids
  • Pregnancy
  • Liver or renal failure
  • Vitamin A hypervitaminosis
  • Severe hyperlipidemia

Tell your doctor about the following if any apply to you:

  • You have relatives with increased levels of lipids in blood and are predisposed to hyperlipidemia
  • You or your relatives suffer from diabetes
  • You are suffering from Alcoholism
  • You are treating a depression

Which adverse effects may manifest when using the medication?

The side effects of Accutane include:

  • Vitamin A hypervitaminosis manifested in the following: dry skin and mucous membranes, haemorrhage in the nasal cavity, hoarseness, conjunctivitis and etc.
  • Skin problems: rash, itching, facial dermatitis, sweatiness, hyperpigmentation, reversible allopecia and etc.
  • Locomotor system: muscle pain, joint pain, hyperostosis, tendonitis
  • CNS: behavior changes, depression, headache, increased intracranial pressure, seizures
  • Sensory organs: decreased vision acuity, photosensibilisation, cataract, decreased hearing , keratitis
  • Gastrointestinal tract: nausea, colitis, GI hemorrhage, rarely hepatitis.
  • Respiratory organs: bronchospasm
  • Haemopoietic system: decreased leukocyte and erythrocyte levels, increase or decrease of thrombocyte levels
  • Immune system: local or systemic infections caused be gram-positive bacteria
  • Other: Hematuria, pancreatitis, vasculitis, lymphadenopathy

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Isotretinoin?

The drug is affected by the following:

  • Vitamin A supplements
  • Corticosteroids
  • Tetracycline antibiotics
  • Epilepsy treatment
  • Oral contraceptives
  • St.John's worth

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient: Accutane is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.