Generic Tiova Rotacap (Tiotropium Bromide)
Tiova Rotacap
Tiova is an anticholinergic agent, it widens breathing passages and is used treat breathing difficulties caused by chronic obstructive pulmonary disease.
Package
Price
Per Bottles
Savings
Bonus
Order
15 caps x 1 bottle
$119.99
$119.99
$0.00
Next orders 10% discount
15 caps x 3 bottles
$299.99
$100.00
$59.97
Next orders 10% discount
Free standard airmail service
Product Description

Common use

Tiova is a specific antagonist of muscarinic receptors with longterm action. It reversibly blocks receptors of M3 type in respiratory track which results in relaxation of smooth muscles of the bronchial tree. High affinity of the receptors and slow release of the inhibitor from the complex with M3 receptor stipulates prolonged local action of Tiovais. Bronholitic effect of the drug results of local action, dose and persisted for at least 24 hours. Effects of Tiova depend on the dose and continues for 24 hours. The medication is used to treat bronchial spasms (wheezing) caused by chronic obstructive pulmonary disease, chronic bronchitis and emphysema.



Dosage and direction

Tiova comes as capsules with powder for inhalations with the HandiHaler inhalation device. Use the medication about the same time each day.



Precautions

Cautiousness is needed in treatment of patients with narrow-angle glaucoma, urination disorders caused by prostatic hypertrophy or obstruction of the bladder neck. Tiovais cannto be used for urgent blockage of a bronchial spasm. Avoid getting of the medication in eyes. Monitoring on a regular basis is needed in the patients with moderate and severe renal failure treated by Tiovais and medications which excreted by the kidneys. Inhaled medications may cause paradoxical bronchospasm and other reactions of such kind. Avoid administration of the medication if you are pregnant or breastfeeding.



Contraindications

Tiova cannot be administered to the patients with hypersensitivity to the medication, atropine and its derivates (ipratropium and oxytropine). Use in adolescents under 18 years of age is not researched.





Possible side effects

Most common side effects include local reactions such as dry mouth, throat pain, coughing, paradoxical bronchospasm. Changes in accommodation if the medication got into the eyes. Allergic reactions (rash, swelling) are possible. In rare were observed cases short heart beat, acute glaucoma, difficulty urination in men with prostatic hypertrophy, constipation.



Drug interactions

Concomitant use of Tiova with other anticholinergetic medications is not recommended.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your doses at about the same time each day to avoid missing a dose.



Overdose

It was not reported about overdose if Tiova was used in therapeutic doses. In case of considerable exceeding of the recommended dose symptoms associated with anticholinergetic properties of the medication are observed: reversible changes in accommodation, dry mouth. Acute poisoning is not likely due to low biological availability of the medication used as inhalations.



Storage

Store at room temperature away from moisture, sunlight, kids and pets in a tight container.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Accutane

Other names used:

  • Roaccutane®

Active Ingredients:

  • Isotretionin

How does Accutane work and what pharmaceutical group does it belong to?

Isotretionin the active ingredient of Accutane belongs to a group of drugs called retinoids, which are used mainly in treatment of skin disorders. The exact mechanism of Accutane is not currently known however it is clinically determined that the drug exerts dose-dependent suppressive effect on the sebaceous glands activity and decreases their size. The drug also expresses anti-inflammatory effect on skin as well as inhibits the formation of comedones. The effects of the drug are temporary however the acne remissions may be controlled.

Which conditions are treated with Isotretinoin?

The drug is indicated in treatment of:

  • Severe cystic acne vulgaris
  • Acne rosacea
  • Hidradenitis suppurativa

What should a patient know before using Accutane?

The Isotretinoin should not be used in cases of:

  • Known hypersensitivity to any components of the preparation or to other retinoids
  • Pregnancy
  • Liver or renal failure
  • Vitamin A hypervitaminosis
  • Severe hyperlipidemia

Tell your doctor about the following if any apply to you:

  • You have relatives with increased levels of lipids in blood and are predisposed to hyperlipidemia
  • You or your relatives suffer from diabetes
  • You are suffering from Alcoholism
  • You are treating a depression

Which adverse effects may manifest when using the medication?

The side effects of Accutane include:

  • Vitamin A hypervitaminosis manifested in the following: dry skin and mucous membranes, haemorrhage in the nasal cavity, hoarseness, conjunctivitis and etc.
  • Skin problems: rash, itching, facial dermatitis, sweatiness, hyperpigmentation, reversible allopecia and etc.
  • Locomotor system: muscle pain, joint pain, hyperostosis, tendonitis
  • CNS: behavior changes, depression, headache, increased intracranial pressure, seizures
  • Sensory organs: decreased vision acuity, photosensibilisation, cataract, decreased hearing , keratitis
  • Gastrointestinal tract: nausea, colitis, GI hemorrhage, rarely hepatitis.
  • Respiratory organs: bronchospasm
  • Haemopoietic system: decreased leukocyte and erythrocyte levels, increase or decrease of thrombocyte levels
  • Immune system: local or systemic infections caused be gram-positive bacteria
  • Other: Hematuria, pancreatitis, vasculitis, lymphadenopathy

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Isotretinoin?

The drug is affected by the following:

  • Vitamin A supplements
  • Corticosteroids
  • Tetracycline antibiotics
  • Epilepsy treatment
  • Oral contraceptives
  • St.John's worth

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient: Accutane is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.